Neovascularization Effects of Carbon Monoxide Releasing Drugs Chemisorbed on Coscinodiscus Diatoms Carriers Characterized by Spectromicroscopy Imaging
نویسندگان
چکیده
منابع مشابه
Biological signaling by carbon monoxide and carbon monoxide-releasing molecules.
Carbon monoxide (CO) is continuously produced in mammalian cells during the degradation of heme. It is a stable gaseous molecule that reacts selectively with transition metals in a specific redox state, and these characteristics restrict the interaction of CO with defined biological targets that transduce its signaling activity. Because of the high affinity of CO for ferrous heme, these targets...
متن کاملCarbon Monoxide Releasing Pharmaceuticals
Carbon monoxide (CO) was ignored by the medical research community for decades, who thought that no biological relevance could emerge from exploring the physiological effects of a gas that had earned itself a reputation over the years as a ‘silent killer’ [2] . The well-known poisoning by carbon monoxide is a result of it binding to Hemoglobin, the oxygen carrier in blood with very high affinit...
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Carbon monoxide (CO) is endogenously produced in the human body, mainly from the oxidation of heme catalyzed by heme oxygenase (HO) enzymes. The induction of HO and the consequent increase in CO production play important physiological roles in vasorelaxation and neurotransmission and in the immune system. The exogenous administration of CO gas and CO-releasing molecules (CO-RMs) has been shown ...
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In this research, a mineral barite powder was reduced by carbon monoxide gas and the effects of reduction time and temperature was investigated as well as barite particle size. Results showed that the best result would be feasible when the barite particle sizes are between (-70 +100) in mesh scale. The barite reduction could reach the maximum level (98%) after reduction by carbon monoxide at 85...
متن کاملCardioprotective actions by a water-soluble carbon monoxide-releasing molecule.
Carbon monoxide, which is generated in mammals during the degradation of heme by the enzyme heme oxygenase, is an important signaling mediator. Transition metal carbonyls have been recently shown to function as carbon monoxide-releasing molecules (CO-RMs) and to elicit distinct pharmacological activities in biological systems. In the present study, we report that a water-soluble form of CO-RM p...
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ژورنال
عنوان ژورنال: Applied Sciences
سال: 2020
ISSN: 2076-3417
DOI: 10.3390/app10207380